The TPM3‐NTRK1 rearrangement is a recurring event in colorectal carcinoma and is associated with tumor sensitivity to TRKA kinase inhibition

The NTRK1 gene encodes Tropomyosin‐related kinase A (TRKA), the high‐affinity Nerve Growth Factor Receptor. NTRK1 was originally isolated from a colorectal carcinoma (CRC) sample as component of a somatic rearrangement (TPM3‐NTRK1) resulting in expression of the oncogenic chimeric protein TPM3‐TRKA,...

সম্পূর্ণ বিবরণ

সংরক্ষণ করুন:
গ্রন্থ-পঞ্জীর বিবরন
প্রকাশিত:Mol Oncol
প্রধান লেখক: Ardini, Elena, Bosotti, Roberta, Borgia, Andrea Lombardi, De Ponti, Cristina, Somaschini, Alessio, Cammarota, Rosaria, Amboldi, Nadia, Raddrizzani, Laura, Milani, Andrea, Magnaghi, Paola, Ballinari, Dario, Casero, Daniele, Gasparri, Fabio, Banfi, Patrizia, Avanzi, Nilla, Saccardo, Maria B., Alzani, Rachele, Bandiera, Tiziano, Felder, Eduard, Donati, Daniele, Pesenti, Enrico, Sartore-Bianchi, Andrea, Gambacorta, Marcello, Pierotti, Marco A., Siena, Salvatore, Veronese, Silvio, Galvani, Arturo, Isacchi, Antonella
বিন্যাস: Artigo
ভাষা:Inglês
প্রকাশিত: John Wiley and Sons Inc. 2014
বিষয়গুলি:
Research Articles
অনলাইন ব্যবহার করুন:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528583/
https://ncbi.nlm.nih.gov/pubmed/24962792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2014.06.001
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