Establishment and genomic characterization of the new chordoma cell line Chor-IN-1

Chordomas are rare, slowly growing tumors with high medical need, arising in the axial skeleton from notochord remnants. The transcription factor “brachyury” represents a distinctive molecular marker and a key oncogenic driver of chordomas. Tyrosine kinase receptors are also expressed, but so far ki...

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Udgivet i:Sci Rep
Main Authors: Bosotti, Roberta, Magnaghi, Paola, Di Bella, Sebastiano, Cozzi, Liviana, Cusi, Carlo, Bozzi, Fabio, Beltrami, Nicola, Carapezza, Giovanni, Ballinari, Dario, Amboldi, Nadia, Lupi, Rosita, Somaschini, Alessio, Raddrizzani, Laura, Salom, Barbara, Galvani, Arturo, Stacchiotti, Silvia, Tamborini, Elena, Isacchi, Antonella
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5569021/
https://ncbi.nlm.nih.gov/pubmed/28835717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10044-3
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