Mining potentially actionable kinase gene fusions in cancer cell lines with the KuNG FU database

Inhibition of kinase gene fusions (KGFs) has proven successful in cancer treatment and continues to represent an attractive research area, due to kinase druggability and clinical validation. Indeed, literature and public databases report a remarkable number of KGFs as potential drug targets, often i...

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Veröffentlicht in:Sci Data
Hauptverfasser: Somaschini, Alessio, Di Bella, Sebastiano, Cusi, Carlo, Raddrizzani, Laura, Leone, Antonella, Carapezza, Giovanni, Mazza, Tommaso, Isacchi, Antonella, Bosotti, Roberta
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7705673/
https://ncbi.nlm.nih.gov/pubmed/33257674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41597-020-00761-2
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