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Mining potentially actionable kinase gene fusions in cancer cell lines with the KuNG FU database

Inhibition of kinase gene fusions (KGFs) has proven successful in cancer treatment and continues to represent an attractive research area, due to kinase druggability and clinical validation. Indeed, literature and public databases report a remarkable number of KGFs as potential drug targets, often i...

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Podrobná bibliografie
Vydáno v:Sci Data
Hlavní autoři: Somaschini, Alessio, Di Bella, Sebastiano, Cusi, Carlo, Raddrizzani, Laura, Leone, Antonella, Carapezza, Giovanni, Mazza, Tommaso, Isacchi, Antonella, Bosotti, Roberta
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7705673/
https://ncbi.nlm.nih.gov/pubmed/33257674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41597-020-00761-2
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