Development of transplantable human chordoma xenograft for preclinical assessment of novel therapeutic strategies

BACKGROUND: Chordomas are rare and indolent bone tumors that arise in the skull base and mobile spine. Distant metastases occur in >20% of cases, but morbidity and mortality are mainly related to local relapses that affect the majority of patients. Standard chemotherapy has modest activity, where...

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Detalhes bibliográficos
Main Authors: Bozzi, Fabio, Manenti, Giacomo, Conca, Elena, Stacchiotti, Silvia, Messina, Antonella, Dagrada, GianPaolo, Gronchi, Alessandro, Panizza, Pietro, Pierotti, Marco A., Tamborini, Elena, Pilotti, Silvana
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3870831/
https://ncbi.nlm.nih.gov/pubmed/24366975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/not152
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