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Development of transplantable human chordoma xenograft for preclinical assessment of novel therapeutic strategies
BACKGROUND: Chordomas are rare and indolent bone tumors that arise in the skull base and mobile spine. Distant metastases occur in >20% of cases, but morbidity and mortality are mainly related to local relapses that affect the majority of patients. Standard chemotherapy has modest activity, where...
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| 主要な著者: | , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3870831/ https://ncbi.nlm.nih.gov/pubmed/24366975 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/not152 |
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