Identification and characterization of a novel SCYL3-NTRK1 rearrangement in a colorectal cancer patient

In colorectal cancer patients, chromosomal rearrangements involving NTRK1 gene (encoding the TRKA protein) are shown in a small subset of patients and are associated with the constitutive activation of the kinase domain of TRKA. In turn, activated TRKA-fusion proteins are associated with proliferati...

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Udgivet i:Oncotarget
Main Authors: Milione, Massimo, Ardini, Elena, Christiansen, Jason, Valtorta, Emanuele, Veronese, Silvio, Bosotti, Roberta, Pellegrinelli, Alessio, Testi, Adele, Pietrantonio, Filippo, Fucà, Giovanni, Wei, Ge, Murphy, Danielle, Siena, Salvatore, Isacchi, Antonella, De Braud, Filippo
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589663/
https://ncbi.nlm.nih.gov/pubmed/28903424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19512
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