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Antibody mediated CDCP1 degradation as mode of action for cancer targeted therapy

CUB‐domain‐containing‐protein‐1 (CDCP1) is an integral membrane protein whose expression is up‐regulated in various cancer types. Although high CDCP1 expression has been correlated with poor prognosis in lung, breast, pancreas, and renal cancer, its functional role in tumor formation or progression...

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Dades bibliogràfiques
Publicat a:Mol Oncol
Autors principals: Kollmorgen, Gwendlyn, Niederfellner, Gerhard, Lifke, Alexander, Spohn, Gloria J., Rieder, Natascha, Vega Harring, Suzana, Bauss, Frieder, Burtscher, Helmut, Lammers, Reiner, Bossenmaier, Birgit
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528444/
https://ncbi.nlm.nih.gov/pubmed/24055141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2013.08.009
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