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Acquired Resistance to Antibody-Drug Conjugates

Antibody-drug conjugates (ADCs) combine the tumor selectivity of antibodies with the potency of cytotoxic small molecules thereby constituting antibody-mediated chemotherapy. As this inherently limits the adverse effects of the chemotherapeutic, such approaches are heavily pursued by pharma and biot...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Collins, Denis M., Bossenmaier, Birgit, Kollmorgen, Gwendlyn, Niederfellner, Gerhard
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6468698/
https://ncbi.nlm.nih.gov/pubmed/30897808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11030394
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