Antibody mediated CDCP1 degradation as mode of action for cancer targeted therapy

CUB‐domain‐containing‐protein‐1 (CDCP1) is an integral membrane protein whose expression is up‐regulated in various cancer types. Although high CDCP1 expression has been correlated with poor prognosis in lung, breast, pancreas, and renal cancer, its functional role in tumor formation or progression...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Kollmorgen, Gwendlyn, Niederfellner, Gerhard, Lifke, Alexander, Spohn, Gloria J., Rieder, Natascha, Vega Harring, Suzana, Bauss, Frieder, Burtscher, Helmut, Lammers, Reiner, Bossenmaier, Birgit
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2013
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528444/
https://ncbi.nlm.nih.gov/pubmed/24055141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2013.08.009
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