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EZH2 regulates the developmental timing of effectors of the pre-antigen receptor checkpoints
The histone methyltransferase EZH2 is required for B and T cell development; however the molecular mechanisms underlying this requirement remain elusive. In a murine model of lymphoid specific EZH2-deficiency we found that EZH2 was required for proper development of adaptive, but not innate, lymphoi...
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| Udgivet i: | J Immunol |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5527689/ https://ncbi.nlm.nih.gov/pubmed/28490575 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700319 |
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