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The transcriptional repressor ID2 supports natural killer cell maturation by controlling TCF1 amplitude

Gaining a mechanistic understanding of the expansion and maturation program of natural killer (NK) cells will provide opportunities for harnessing their inflammation-inducing and oncolytic capacity for therapeutic purposes. Here, we demonstrated that ID2, a transcriptional regulatory protein constit...

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Publicat a:J Exp Med
Autors principals: Li, Zhong-Yin, Morman, Rosemary E., Hegermiller, Emma, Sun, Mengxi, Bartom, Elizabeth T., Maienschein-Cline, Mark, Sigvardsson, Mikael, Kee, Barbara L.
Format: Artigo
Idioma:Inglês
Publicat: Rockefeller University Press 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8056751/
https://ncbi.nlm.nih.gov/pubmed/33857289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20202032
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