Transcription factor ID2 prevents E proteins from enforcing a naïve T lymphocyte gene program during NK cell development

All innate lymphoid cells (ILC) require the small helix-loop-helix transcription factor ID2 but the functions of ID2 are not well understood in these cells. Here we show that mature natural killer (NK) cells, the prototypic ILC, developed in mice lacking ID2 but remained as precursor CD27(+)CD11b(−)...

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Bibliografski detalji
Izdano u:Sci Immunol
Glavni autori: Zook, Erin C., Li, Zhong-Yin, Xu, Yiying, de Pooter, Renée F., Verykokakis, Mihalis, Beaulieu, Aimee, Lasorella, Anna, Maienschein-Cline, Mark, Sun, Joseph C., Sigvardsson, Mikael, Kee, Barbara L.
Format: Artigo
Jezik:Inglês
Izdano: 2018
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6750718/
https://ncbi.nlm.nih.gov/pubmed/29703840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.aao2139
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