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Mitotic chromosomal instability and cancer: mouse modelling of the human disease
The stepwise progression from an early dysplastic lesion to full-blown metastatic malignancy is associated with increases in genomic instability. Mitotic chromosomal instability — the inability to faithfully segregate equal chromosome complements to two daughter cells during mitosis — is a widesprea...
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| Pubblicato in: | Nat Rev Cancer |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5526619/ https://ncbi.nlm.nih.gov/pubmed/20094045 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc2781 |
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