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Very CIN-ful: Whole Chromosome Instability Promotes Tumor Suppressor Loss of Heterozygosity
Mechanisms by which whole chromosome instability lead to tumorigenesis have eluded the cancer research field. In this issue of Cancer Cell, Baker et al. show that CIN induced by a defective mitotic checkpoint, under certain genetic and tissue contexts, leads to accelerated loss of heterozygosity of...
में बचाया:
| में प्रकाशित: | Cancer Cell |
|---|---|
| मुख्य लेखकों: | , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2009
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5513159/ https://ncbi.nlm.nih.gov/pubmed/19962661 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2009.11.014 |
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