Caricamento...

Very CIN-ful: Whole Chromosome Instability Promotes Tumor Suppressor Loss of Heterozygosity

Mechanisms by which whole chromosome instability lead to tumorigenesis have eluded the cancer research field. In this issue of Cancer Cell, Baker et al. show that CIN induced by a defective mitotic checkpoint, under certain genetic and tissue contexts, leads to accelerated loss of heterozygosity of...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Cancer Cell
Autori principali: Sotillo, Rocio, Schvartzman, Juan-Manuel, Benezra, Robert
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5513159/
https://ncbi.nlm.nih.gov/pubmed/19962661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2009.11.014
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !