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Mad2-induced chromosome instability leads to lung tumor relapse after oncogene withdrawal

Inhibition of an initiating oncogene often leads to extensive tumor cell death, a phenomenon known as oncogene addiction1. This has led to the search for compounds that specifically target and inhibit oncogenes as anti-cancer agents. Whether chromosomal instability (CIN) generated as a result of der...

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Detaylı Bibliyografya
Asıl Yazarlar: Sotillo, Rocio, Schvartzman, Juan-Manuel, Socci, Nicholas D., Benezra, Robert
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2841716/
https://ncbi.nlm.nih.gov/pubmed/20173739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08803
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