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Mad2-induced chromosome instability leads to lung tumor relapse after oncogene withdrawal
Inhibition of an initiating oncogene often leads to extensive tumor cell death, a phenomenon known as oncogene addiction1. This has led to the search for compounds that specifically target and inhibit oncogenes as anti-cancer agents. Whether chromosomal instability (CIN) generated as a result of der...
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| Principais autores: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2841716/ https://ncbi.nlm.nih.gov/pubmed/20173739 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08803 |
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