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Quantification of tumour evolution and heterogeneity via Bayesian epiallele detection
BACKGROUND: Epigenetic heterogeneity within a tumour can play an important role in tumour evolution and the emergence of resistance to treatment. It is increasingly recognised that the study of DNA methylation (DNAm) patterns along the genome – so-called ‘epialleles’ – offers greater insight into ep...
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| Publicado en: | BMC Bioinformatics |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
BioMed Central
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5526259/ https://ncbi.nlm.nih.gov/pubmed/28743252 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-017-1753-2 |
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