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Tumour heterogeneity and the evolution of polyclonal drug resistance

Cancer drug resistance is a major problem, with the majority of patients with metastatic disease ultimately developing multidrug resistance and succumbing to their disease. Our understanding of molecular events underpinning treatment failure has been enhanced by new genomic technologies and pre‐clin...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Burrell, Rebecca A., Swanton, Charles
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528620/
https://ncbi.nlm.nih.gov/pubmed/25087573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2014.06.005
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