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Tumour heterogeneity and the evolution of polyclonal drug resistance

Cancer drug resistance is a major problem, with the majority of patients with metastatic disease ultimately developing multidrug resistance and succumbing to their disease. Our understanding of molecular events underpinning treatment failure has been enhanced by new genomic technologies and pre‐clin...

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Bibliographic Details
Published in:Mol Oncol
Main Authors: Burrell, Rebecca A., Swanton, Charles
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528620/
https://ncbi.nlm.nih.gov/pubmed/25087573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2014.06.005
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