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Phylogenetic Quantification of Intra-tumour Heterogeneity
Intra-tumour genetic heterogeneity is the result of ongoing evolutionary change within each cancer. The expansion of genetically distinct sub-clonal populations may explain the emergence of drug resistance, and if so, would have prognostic and predictive utility. However, methods for objectively qua...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3990475/ https://ncbi.nlm.nih.gov/pubmed/24743184 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003535 |
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