Intra-tumour genetic heterogeneity and poor chemoradiotherapy response in cervical cancer

BACKGROUND: Intra-tumour genetic heterogeneity has been reported in both leukaemias and solid tumours and is implicated in the development of drug resistance in CML and AML. The role of genetic heterogeneity in drug response in solid tumours is unknown. METHODS: To investigate intra-tumour genetic h...

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Detalhes bibliográficos
Main Authors: Cooke, S L, Temple, J, MacArthur, S, Zahra, M A, Tan, L T, Crawford, R A F, Ng, C K Y, Jimenez-Linan, M, Sala, E, Brenton, J D
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Genetics and Genomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031882/
https://ncbi.nlm.nih.gov/pubmed/21063398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605971
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