CDKL5 localizes at the centrosome and midbody and is required for faithful cell division

The cyclin-dependent kinase-like 5 (CDKL5) gene has been associated with rare neurodevelopmental disorders characterized by the early onset of seizures and intellectual disability. The CDKL5 protein is widely expressed in most tissues and cells with both nuclear and cytoplasmic localization. In post...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Barbiero, Isabella, Valente, Davide, Chandola, Chetan, Magi, Fiorenza, Bergo, Anna, Monteonofrio, Laura, Tramarin, Marco, Fazzari, Maria, Soddu, Silvia, Landsberger, Nicoletta, Rinaldo, Cinzia, Kilstrup-Nielsen, Charlotte
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5524905/
https://ncbi.nlm.nih.gov/pubmed/28740074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05875-z
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