Synaptic Synthesis, Dephosphorylation, and Degradation: A NOVEL PARADIGM FOR AN ACTIVITY-DEPENDENT NEURONAL CONTROL OF CDKL5

Mutations in the X-linked CDKL5 (cyclin-dependent kinase-like 5) gene have been associated with several forms of neurodevelopmental disorders, including atypical Rett syndrome, autism spectrum disorders, and early infantile epileptic encephalopathy. Accordingly, loss of CDKL5 in mice results in auti...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Biol Chem
Egile Nagusiak: La Montanara, Paolo, Rusconi, Laura, Locarno, Albina, Forti, Lia, Barbiero, Isabella, Tramarin, Marco, Chandola, Chetan, Kilstrup-Nielsen, Charlotte, Landsberger, Nicoletta
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2015
Gaiak:
Neurobiology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4326854/
https://ncbi.nlm.nih.gov/pubmed/25555910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.589762
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