Synaptic Synthesis, Dephosphorylation, and Degradation: A NOVEL PARADIGM FOR AN ACTIVITY-DEPENDENT NEURONAL CONTROL OF CDKL5

Mutations in the X-linked CDKL5 (cyclin-dependent kinase-like 5) gene have been associated with several forms of neurodevelopmental disorders, including atypical Rett syndrome, autism spectrum disorders, and early infantile epileptic encephalopathy. Accordingly, loss of CDKL5 in mice results in auti...

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Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: La Montanara, Paolo, Rusconi, Laura, Locarno, Albina, Forti, Lia, Barbiero, Isabella, Tramarin, Marco, Chandola, Chetan, Kilstrup-Nielsen, Charlotte, Landsberger, Nicoletta
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2015
Konular:
Neurobiology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4326854/
https://ncbi.nlm.nih.gov/pubmed/25555910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.589762
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