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CDKL5 localizes at the centrosome and midbody and is required for faithful cell division

The cyclin-dependent kinase-like 5 (CDKL5) gene has been associated with rare neurodevelopmental disorders characterized by the early onset of seizures and intellectual disability. The CDKL5 protein is widely expressed in most tissues and cells with both nuclear and cytoplasmic localization. In post...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Barbiero, Isabella, Valente, Davide, Chandola, Chetan, Magi, Fiorenza, Bergo, Anna, Monteonofrio, Laura, Tramarin, Marco, Fazzari, Maria, Soddu, Silvia, Landsberger, Nicoletta, Rinaldo, Cinzia, Kilstrup-Nielsen, Charlotte
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5524905/
https://ncbi.nlm.nih.gov/pubmed/28740074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05875-z
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