HIPK2 Is Required for Midbody Remnant Removal Through Autophagy-Mediated Degradation

At the end of abscission, the residual midbody forms the so-called midbody remnant (MBR), a platform affecting cell fate with emerging key role in differentiation, development, and tumorigenicity. Depending on cell type and pathophysiological context, MBRs undergo different outcomes: they can be ret...

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Bibliographische Detailangaben
Veröffentlicht in:Front Cell Dev Biol
Hauptverfasser: Sardina, Francesca, Monteonofrio, Laura, Ferrara, Manuela, Magi, Fiorenza, Soddu, Silvia, Rinaldo, Cinzia
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Cell and Developmental Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7525647/
https://ncbi.nlm.nih.gov/pubmed/33043004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.572094
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