Transfer, analysis, and reversion of the fibrous dysplasia cellular phenotype in human skeletal progenitors

Human skeletal progenitors were engineered to stably express R201C mutated, constitutively active Gsα using lentiviral vectors. Long‐term transduced skeletal progenitors were characterized by an enhanced production of cAMP, indicating the transfer of the fundamental cellular phenotype caused by acti...

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Detalhes bibliográficos
Publicado no:J Bone Miner Res
Main Authors: Piersanti, Stefania, Remoli, Cristina, Saggio, Isabella, Funari, Alessia, Michienzi, Stefano, Sacchetti, Benedetto, Robey, Pamela Gehron, Riminucci, Mara, Bianco, Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2009
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5524372/
https://ncbi.nlm.nih.gov/pubmed/19874199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1359/jbmr.091036
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