Skeletal progenitors and the GNAS gene: fibrous dysplasia of bone read through stem cells

Activating mutations of the GNAS gene, which causes fibrous dysplasia of bone (FD), lead to remarkable changes in the properties of skeletal progenitors, and it is these changes that mediate the pathological effect of this gene on bone. Mutated skeletal stem cells lose the ability to differentiate i...

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Hlavní autoři: Riminucci, Mara, Robey, Pamela Gehron, Saggio, Isabella, Bianco, Paolo
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3384548/
https://ncbi.nlm.nih.gov/pubmed/20841428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1677/JME-10-0097
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