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Skeletal progenitors and the GNAS gene: fibrous dysplasia of bone read through stem cells
Activating mutations of the GNAS gene, which causes fibrous dysplasia of bone (FD), lead to remarkable changes in the properties of skeletal progenitors, and it is these changes that mediate the pathological effect of this gene on bone. Mutated skeletal stem cells lose the ability to differentiate i...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3384548/ https://ncbi.nlm.nih.gov/pubmed/20841428 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1677/JME-10-0097 |
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