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Age‐Dependent Demise of GNAS‐Mutated Skeletal Stem Cells and “Normalization” of Fibrous Dysplasia of Bone
We studied the role of somatic mosaicism in fibrous dysplasia of bone (FD) within the context of skeletal (“mesenchymal”) stem cells by assessing the frequency of mutated colony forming unit‐fibroblasts (CFU‐Fs) from FD lesions, and in some cases, from unaffected sites, in a series of patients. Ther...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons and The American Society for Bone and Mineral Research (ASBMR)
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2585500/ https://ncbi.nlm.nih.gov/pubmed/18597624 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1359/jbmr.080609 |
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