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Age‐Dependent Demise of GNAS‐Mutated Skeletal Stem Cells and “Normalization” of Fibrous Dysplasia of Bone

We studied the role of somatic mosaicism in fibrous dysplasia of bone (FD) within the context of skeletal (“mesenchymal”) stem cells by assessing the frequency of mutated colony forming unit‐fibroblasts (CFU‐Fs) from FD lesions, and in some cases, from unaffected sites, in a series of patients. Ther...

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Bibliografische gegevens
Hoofdauteurs: Kuznetsov, Sergei A, Cherman, Natasha, Riminucci, Mara, Collins, Michael T, Robey, Pamela Gehron, Bianco, Paolo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons and The American Society for Bone and Mineral Research (ASBMR) 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2585500/
https://ncbi.nlm.nih.gov/pubmed/18597624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1359/jbmr.080609
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