Transfer, analysis, and reversion of the fibrous dysplasia cellular phenotype in human skeletal progenitors

Human skeletal progenitors were engineered to stably express R201C mutated, constitutively active Gsα using lentiviral vectors. Long‐term transduced skeletal progenitors were characterized by an enhanced production of cAMP, indicating the transfer of the fundamental cellular phenotype caused by acti...

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Détails bibliographiques
Publié dans:J Bone Miner Res
Auteurs principaux: Piersanti, Stefania, Remoli, Cristina, Saggio, Isabella, Funari, Alessia, Michienzi, Stefano, Sacchetti, Benedetto, Robey, Pamela Gehron, Riminucci, Mara, Bianco, Paolo
Format: Artigo
Langue:Inglês
Publié: Wiley Subscription Services, Inc., A Wiley Company 2009
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5524372/
https://ncbi.nlm.nih.gov/pubmed/19874199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1359/jbmr.091036
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