Transfer, analysis, and reversion of the fibrous dysplasia cellular phenotype in human skeletal progenitors

Human skeletal progenitors were engineered to stably express R201C mutated, constitutively active Gsα using lentiviral vectors. Long‐term transduced skeletal progenitors were characterized by an enhanced production of cAMP, indicating the transfer of the fundamental cellular phenotype caused by acti...

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Publicat a:J Bone Miner Res
Autors principals: Piersanti, Stefania, Remoli, Cristina, Saggio, Isabella, Funari, Alessia, Michienzi, Stefano, Sacchetti, Benedetto, Robey, Pamela Gehron, Riminucci, Mara, Bianco, Paolo
Format: Artigo
Idioma:Inglês
Publicat: Wiley Subscription Services, Inc., A Wiley Company 2009
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5524372/
https://ncbi.nlm.nih.gov/pubmed/19874199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1359/jbmr.091036
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