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Skeletal progenitors and the GNAS gene: fibrous dysplasia of bone read through stem cells

Activating mutations of the GNAS gene, which causes fibrous dysplasia of bone (FD), lead to remarkable changes in the properties of skeletal progenitors, and it is these changes that mediate the pathological effect of this gene on bone. Mutated skeletal stem cells lose the ability to differentiate i...

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Bibliografiska uppgifter
Huvudupphovsmän: Riminucci, Mara, Robey, Pamela Gehron, Saggio, Isabella, Bianco, Paolo
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3384548/
https://ncbi.nlm.nih.gov/pubmed/20841428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1677/JME-10-0097
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