Regulation of miR-483-3p by the O-linked N-acetylglucosamine transferase links chemosensitivity to glucose metabolism in liver cancer cells

The miR-483-3p is upregulated in several tumors, including liver tumors, where it inhibits TP53-dependent apoptosis by targeting the pro-apoptotic gene BBC3/PUMA. The transcriptional regulation of the miR-483-3p could be driven by the β-catenin/USF1 complex, independently from its host gene IGF2, an...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Oncogenesis
Главные авторы: Pepe, F, Pagotto, S, Soliman, S, Rossi, C, Lanuti, P, Braconi, C, Mariani-Costantini, R, Visone, R, Veronese, A
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2017
Предметы:
Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5523068/
https://ncbi.nlm.nih.gov/pubmed/28481368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2017.35
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы