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The Glucose-Regulated MiR-483-3p Influences Key Signaling Pathways in Cancer
The hsa-mir-483 gene, located within the IGF2 locus, transcribes for two mature microRNAs, miR-483-5p and miR-483-3p. This gene, whose regulation is mediated by the the CTNNB1/USF1 complex, shows an independent expression from its host gene IGF2. The miR-483-3p affects the Wnt/β-catenin, the TGF-β,...
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Publié dans: | Cancers (Basel) |
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Auteurs principaux: | , , |
Format: | Artigo |
Langue: | Inglês |
Publié: |
MDPI
2018
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6025222/ https://ncbi.nlm.nih.gov/pubmed/29867024 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers10060181 |
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