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The Glucose-Regulated MiR-483-3p Influences Key Signaling Pathways in Cancer

The hsa-mir-483 gene, located within the IGF2 locus, transcribes for two mature microRNAs, miR-483-5p and miR-483-3p. This gene, whose regulation is mediated by the the CTNNB1/USF1 complex, shows an independent expression from its host gene IGF2. The miR-483-3p affects the Wnt/β-catenin, the TGF-β,...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Pepe, Felice, Visone, Rosa, Veronese, Angelo
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6025222/
https://ncbi.nlm.nih.gov/pubmed/29867024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers10060181
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