Oncogenic Role of miR-483-3p at the IGF2/483 Locus

hsa-mir-483 is located within intron 2 of the IGF2 locus. We found that the mature microRNA (miRNA) miR-483-3p is overexpressed in 100% of Wilms’ tumors. In addition, colon, breast, and liver cancers exhibit high or even extremely high levels of miR-483-3p in ~30% of the cases. A coregulation with I...

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Gepubliceerd in:Cancer Res
Hoofdauteurs: Veronese, Angelo, Lupini, Laura, Consiglio, Jessica, Visone, Rosa, Ferracin, Manuela, Fornari, Francesca, Zanesi, Nicola, Alder, Hansjuerg, D’Elia, Gemma, Gramantieri, Laura, Bolondi, Luigi, Lanza, Giovanni, Querzoli, Patrizia, Angioni, Adriano, Croce, Carlo M., Negrini, Massimo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303586/
https://ncbi.nlm.nih.gov/pubmed/20388800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-4456
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