Mutated β-catenin evades a microRNA-dependent regulatory loop

hsa-mir-483 is located within intron 2 of the IGF2 gene. We have previously shown oncogenic features of miR-483-3p through cooperation with IGF2 or by independently targeting the proapoptotic gene BBC3/PUMA. Here we demonstrate that expression of miR-483 can be induced independently of IGF2 by the o...

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Bibliografski detalji
Glavni autori: Veronese, Angelo, Visone, Rosa, Consiglio, Jessica, Acunzo, Mario, Lupini, Laura, Kim, Taewan, Ferracin, Manuela, Lovat, Francesca, Miotto, Elena, Balatti, Veronica, D'Abundo, Lucilla, Gramantieri, Laura, Bolondi, Luigi, Pekarsky, Yuri, Perrotti, Danilo, Negrini, Massimo, Croce, Carlo M.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2011
Teme:
Biological Sciences
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064338/
https://ncbi.nlm.nih.gov/pubmed/21383185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1101734108
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