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UHRF1 promotes breast cancer progression by suppressing KLF17 expression by hypermethylating its promoter

UHRF1 is an epigenetic regulator and perform pivotal functions in cell tumorigenesis. We found UHRF1 is increased in breast cancer and patients with high UHRF1 levels have poorer prognoses than those with low UHRF1 levels. However, the underlying mechanisms remain largely unknown. Here, we found ove...

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Podrobná bibliografie
Vydáno v:Am J Cancer Res
Hlavní autoři: Gao, Shui-Ping, Sun, He-Fen, Li, Liang-Dong, Fu, Wen-Yan, Jin, Wei
Médium: Artigo
Jazyk:Inglês
Vydáno: e-Century Publishing Corporation 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5523035/
https://ncbi.nlm.nih.gov/pubmed/28744404
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