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Promoter Hypermethylation of KLF4 Inactivates Its Tumor Suppressor Function in Cervical Carcinogenesis

OBJECTIVE: The KLF4 gene has been shown to be inactivated in cervical carcinogenesis as a tumor suppressor. However, the mechanism of KLF4 silencing in cervical carcinomas has not yet been identified. DNA methylation plays a key role in stable suppression of gene expression. METHODS: The methylation...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Yang, Wen-Ting, Zheng, Peng-Sheng
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3925171/
https://ncbi.nlm.nih.gov/pubmed/24551169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0088827
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