Ras Promotes Growth by Alternative Splicing-Mediated Inactivation of the KLF6 Tumor Suppressor in Hepatocellular Carcinoma

BACKGROUND & AIMS: HCC is the 5(th) most prevalent cancer worldwide and the 3(rd) most lethal. Dysregulation of alternative splicing underlies a number of human diseases, yet its contribution to liver cancer has not been fully explored. The KLF6 gene is a zinc finger transcription factor that in...

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Detalhes bibliográficos
Main Authors: Yea, Steven, Narla, Goutham, Zhao, Xiao, Garg, Rakhi, Tal-Kremer, Sigal, Hod, Eldad, Villanueva, Augusto, Loke, Johnny, Tarocchi, Mirko, Akita, Kunihara, Shirasawa, Senji, Sasazuki, Takehiko, Martignetti, John A, Llovet, Josep M, Friedman, Scott L
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2600656/
https://ncbi.nlm.nih.gov/pubmed/18471523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2008.02.015
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