Germline promoter hypermethylation of tumor suppressor genes in gastric cancer

AIM: To explore germline hypermethylation of the tumor suppressor genes MLH1, CDH1 and P16(INK4a) in suspected cases of hereditary gastric cancer (GC). METHODS: A group of 140 Chinese GC patients in whom the primary cancer had developed before the age of 60 or who had a familial history of cancer we...

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Autors principals: Wu, Pu-Yuan, Zhang, Zheng, Wang, Jing-Mei, Guo, Wen-Wen, Xiao, Nong, He, Qiong, Wang, Ya-Ping, Fan, Yi-Mei
Format: Artigo
Idioma:Inglês
Publicat: Baishideng Publishing Group Co., Limited 2012
Matèries:
Brief Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251808/
https://ncbi.nlm.nih.gov/pubmed/22228973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v18.i1.70
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