TFPI-2 is a putative tumor suppressor gene frequently inactivated by promoter hypermethylation in nasopharyngeal carcinoma

BACKGROUND: Epigenetic silencing of tumor suppressor genes play important roles in NPC tumorgenesis. Tissue factor pathway inhibitor-2 (TFPI-2), is a protease inhibitor. Recently, TFPI-2 was suggested to be a tumor suppressor gene involved in tumorigenesis and metastasis in some cancers. In this stu...

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Bibliografski detalji
Glavni autori: Wang, Shumin, Xiao, Xue, Zhou, Xiaoying, Huang, Tingting, Du, Chunping, Yu, Nana, Mo, Yingxi, Lin, Longde, Zhang, Jinyan, Ma, Ning, Murata, Mariko, Huang, Guangwu, Zhang, Zhe
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2010
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2992524/
https://ncbi.nlm.nih.gov/pubmed/21062455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-617
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