Putative tumour-suppressor gene DAB2 is frequently down regulated by promoter hypermethylation in nasopharyngeal carcinoma

BACKGROUND: Human Disabled-2 (DAB2), is a multi-function signalling molecule that it is frequently down-regulated in human cancers. We aimed to investigate the possible tumour suppressor effect of DAB2 in nasopharyngeal carcinoma (NPC). METHODS: We studied the expression of DAB2 in NPC cell lines, x...

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Autors principals: Tong, Joanna H, Ng, David C, Chau, Shuk L, So, Ken K, Leung, Patrick P, Lee, Tin L, Lung, Raymond W, Chan, Michael W, Chan, Anthony W, Lo, Kwok W, To, Ka F
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2891638/
https://ncbi.nlm.nih.gov/pubmed/20525238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-253
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