Putative tumour-suppressor gene DAB2 is frequently down regulated by promoter hypermethylation in nasopharyngeal carcinoma

BACKGROUND: Human Disabled-2 (DAB2), is a multi-function signalling molecule that it is frequently down-regulated in human cancers. We aimed to investigate the possible tumour suppressor effect of DAB2 in nasopharyngeal carcinoma (NPC). METHODS: We studied the expression of DAB2 in NPC cell lines, x...

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Main Authors: Tong, Joanna H, Ng, David C, Chau, Shuk L, So, Ken K, Leung, Patrick P, Lee, Tin L, Lung, Raymond W, Chan, Michael W, Chan, Anthony W, Lo, Kwok W, To, Ka F
格式: Artigo
語言:Inglês
出版: BioMed Central 2010
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2891638/
https://ncbi.nlm.nih.gov/pubmed/20525238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-253
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