Candidate Tumor-Suppressor Gene DLEC1 Is Frequently Downregulated by Promoter Hypermethylation and Histone Hypoacetylation in Human Epithelial Ovarian Cancer

Suppression of ovarian tumor growth by chromosome 3p was demonstrated in a previous study. Deleted in Lung and Esophageal Cancer 1 (DLEC1) on 3p22.3 is a candidate tumor suppressor in lung, esophageal, and renal cancers. The potential involvement of DLEC1 in epithelial ovarian cancer remains unknown...

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Detalhes bibliográficos
Main Authors: Kwong, Joseph, Lee, Ji-Young, Wong, Kwong-Kwok, Zhou, Xiaofeng, Wong, David T W, Lo, Kwok-Wai, Welch, William R, Berkowitz, Ross S, Mok, Samuel C
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2006
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1600675/
https://ncbi.nlm.nih.gov/pubmed/16756719
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