DNA Hypermethylation and Histone Modifications Downregulate the Candidate Tumor Suppressor Gene RRP22 on 22q12 in Human Gliomas

RRP22 (Ras‐related protein on chromosome 22) has been suggested as a candidate tumor suppressor in human cancers. Investigating a panel of 70 human gliomas, we found a frequent decrease in the RRP22 mRNA expression levels (67%), preferentially in high‐grade gliomas [World Health Organization (WHO) g...

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Bibliografische gegevens
Gepubliceerd in:Brain Pathol
Hoofdauteurs: Schmidt, Natalie, Windmann, Sonja, Reifenberger, Guido, Riemenschneider, Markus J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Blackwell Publishing Ltd 2011
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Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8028980/
https://ncbi.nlm.nih.gov/pubmed/21631628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2011.00507.x
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