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UHRF1 promotes breast cancer progression by suppressing KLF17 expression by hypermethylating its promoter

UHRF1 is an epigenetic regulator and perform pivotal functions in cell tumorigenesis. We found UHRF1 is increased in breast cancer and patients with high UHRF1 levels have poorer prognoses than those with low UHRF1 levels. However, the underlying mechanisms remain largely unknown. Here, we found ove...

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Pubblicato in:Am J Cancer Res
Autori principali: Gao, Shui-Ping, Sun, He-Fen, Li, Liang-Dong, Fu, Wen-Yan, Jin, Wei
Natura: Artigo
Lingua:Inglês
Pubblicazione: e-Century Publishing Corporation 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5523035/
https://ncbi.nlm.nih.gov/pubmed/28744404
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