Platelet releasates promote the proliferation of hepatocellular carcinoma cells by suppressing the expression of KLF6

Platelets in the primary tumor microenvironment play crucial roles in the regulation of tumor progression, but the mechanisms underlying are poorly understood. Here, we report that platelet releasates exerted a proliferative effect on hepatocellular carcinoma (HCC) cells both in vitro and in vivo. T...

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Enregistré dans:
Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: He, Ao-Di, Xie, Wen, Song, Wei, Ma, Yuan-Yuan, Liu, Gang, Liang, Ming-Lu, Da, Xing-Wen, Yao, Guang-Qiang, Zhang, Bi-xiang, Gao, Cun-Ji, Xiang, Ji-zhou, Ming, Zhang-Yin
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2017
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5479859/
https://ncbi.nlm.nih.gov/pubmed/28638139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02801-1
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