Platelet releasates promote the proliferation of hepatocellular carcinoma cells by suppressing the expression of KLF6

Platelets in the primary tumor microenvironment play crucial roles in the regulation of tumor progression, but the mechanisms underlying are poorly understood. Here, we report that platelet releasates exerted a proliferative effect on hepatocellular carcinoma (HCC) cells both in vitro and in vivo. T...

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Pubblicato in:Sci Rep
Autori principali: He, Ao-Di, Xie, Wen, Song, Wei, Ma, Yuan-Yuan, Liu, Gang, Liang, Ming-Lu, Da, Xing-Wen, Yao, Guang-Qiang, Zhang, Bi-xiang, Gao, Cun-Ji, Xiang, Ji-zhou, Ming, Zhang-Yin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5479859/
https://ncbi.nlm.nih.gov/pubmed/28638139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02801-1
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