Eukaryotic topoisomerases recognize nucleic acid topology by preferentially interacting with DNA crossovers.

Eukaryotic topoisomerases recognize DNA topology and preferentially react with positively or negatively supercoiled molecules over relaxed substrates. To elucidate the mechanism of this recognition, we examined the interaction of topoisomerases with DNA by electron microscopy. Under all conditions e...

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Bibliografiska uppgifter

I publikationen:	EMBO J
Huvudupphov:	Zechiedrich, E L, Osheroff, N
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	Nature Publishing Group 1990
Ämnen:	Research Article
Länkar:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC552253/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2176156/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1990.tb07908.x
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