Eukaryotic topoisomerases recognize nucleic acid topology by preferentially interacting with DNA crossovers.

Eukaryotic topoisomerases recognize DNA topology and preferentially react with positively or negatively supercoiled molecules over relaxed substrates. To elucidate the mechanism of this recognition, we examined the interaction of topoisomerases with DNA by electron microscopy. Under all conditions e...

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Detalhes bibliográficos

Publicado no:	EMBO J
Principais autores:	Zechiedrich, E L, Osheroff, N
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC552253/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2176156/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1990.tb07908.x
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