Eukaryotic topoisomerases recognize nucleic acid topology by preferentially interacting with DNA crossovers.

Eukaryotic topoisomerases recognize DNA topology and preferentially react with positively or negatively supercoiled molecules over relaxed substrates. To elucidate the mechanism of this recognition, we examined the interaction of topoisomerases with DNA by electron microscopy. Under all conditions e...

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Bibliografiske detaljer

Udgivet i:	EMBO J
Principais autores:	Zechiedrich, E L, Osheroff, N
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Publishing Group 1990
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC552253/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2176156/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1990.tb07908.x
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