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Sonic Hedgehog activates Phospholipase A2 to enhance Smoothened ciliary translocation
The G protein-coupled receptor Smoothened (Smo) is the signal transducer of the Sonic Hedgehog (Shh) pathway. Smo signals through G protein-dependent and independent routes, with G protein-independent canonical signaling to Gli effectors requiring Smo accumulation in the primary cilium. Mechanisms c...
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| Publicat a: | Cell Rep |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5520665/ https://ncbi.nlm.nih.gov/pubmed/28591579 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.05.033 |
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