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Sonic Hedgehog activates Phospholipase A2 to enhance Smoothened ciliary translocation
The G protein-coupled receptor Smoothened (Smo) is the signal transducer of the Sonic Hedgehog (Shh) pathway. Smo signals through G protein-dependent and independent routes, with G protein-independent canonical signaling to Gli effectors requiring Smo accumulation in the primary cilium. Mechanisms c...
Shranjeno v:
| izdano v: | Cell Rep |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2017
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5520665/ https://ncbi.nlm.nih.gov/pubmed/28591579 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.05.033 |
| Oznake: |
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